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Safety questions plague bowel-disease drug fast-tracked by FDA

...total of 49 patients developed ischemic colitis, a potentially life-threatening...study of the drug's link to ischemic colitis, the agency approved the pill...serious adverse-event reports of ischemic colitis and severe constipation associated...

http://brainerddispatch.com/stories/110200/hea_1102000005.shtml
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FDA plans to bring back controversial drug

...suspect in dozens of cases of ischemic colitis, the complication that can...the product labeling said that ischemic colitis had occurred "infrequently...taking Lotronex were at risk of ischemic colitis. But within the last several...

http://brainerddispatch.com/stories/053001/hea_0530010007.shtml
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Drug Lotronex's re-approval greeted by cheers, resistance

...records from the drug's maker, GlaxoSmithKline, died as a result of taking it. Eighty-five people developed ischemic colitis, an inflammation of the colon that occurs when blood flow is interrupted. Another 113 developed constipation so...

http://brainerddispatch.com/stories/062502/hea_0625020009.shtml
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